Managing a case of extensively drug-resistant (XDR) pulmonary tuberculosis in Singapore
Annals of the Academy of Medicine, Singapore
;
: 132-135, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-237328
ABSTRACT
<p><b>INTRODUCTION</b>Extensively drug-resistant tuberculosis (XDR-TB) is an emerging global health risk. We present the first case report of XDR-TB in Singapore.</p><p><b>CLINICAL PICTURE</b>A 41-year-old Indonesian lady with previously treated pulmonary tuberculosis presented with chronic cough. Her sputum was strongly acid-fast bacilli positive and grew Mycobacterium tuberculosis complex resistant to first and second-line TB medications.</p><p><b>TREATMENT</b>She received 5 months of intensive multidrug treatment without sputum smear conversion. She then underwent resection of the diseased lung. The total cost incurred amounted to over S$100,000.</p><p><b>OUTCOME</b>She achieved sputum smear/culture conversion post-surgery, but will require further medical therapy for at least 18 months.</p><p><b>CONCLUSION</b>XDRTB is poorly responsive to therapy and extremely expensive to manage. Its prevention by strict compliance to therapy is paramount.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Singapura
/
Escarro
/
Tuberculose Pulmonar
/
Testes de Sensibilidade Microbiana
/
Terapia Diretamente Observada
/
Farmacorresistência Bacteriana Múltipla
/
Delírio
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Quimioterapia Combinada
Limite:
Adulto
/
Feminino
/
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Annals of the Academy of Medicine, Singapore
Ano de publicação:
2011
Tipo de documento:
Artigo
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