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Analysis and test of piezoelectric micropump for drug delivery / 生物医学工程学杂志
Journal of Biomedical Engineering ; (6): 809-813, 2005.
Artigo em Chinês | WPRIM | ID: wpr-238335
ABSTRACT
With a microsystem or micropump, the release rate of drug delivery is able to be controlled easily to maintain the therapeutic efficacy. A piezoelectric membrane-valve micropump for implantable and carryhome drug delivery system is developed and tested. The influence elements of dynamic performance of the PZT actuator and valve were analyzed, and the calculation method of resonant frequency of the membrane valve was provided. Study results showed that the output performance of the micropump depended on the coupling effect of the actuator and valve. For a given actuator, the output value and the optimal frequency of a micropump could be enhanced only by valve design. Two micropumps with different valve dimensions were fabricated for comparing examination. The smaller -valve micropump obtained higher output values (the maximum flow rate and backpressure being 3.5 ml/min and 27 KPa, respectively) and two optimal frequencies (800 Hz and 3 000 Hz). The larger -valve micropump achieved lower output values (the maximum flow rate and backpressure being 3.0 ml/min and 9 KPa, respectively) and one optimal frequency (about 200 Hz). The test results suggest that the output values and optimal frequency of micropump can be improved by changing the valve dimension, and the viewpoint that checkvalve micropump works only with low acting frequency is wrong.
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Bombas de Infusão Implantáveis / Sistemas de Liberação de Medicamentos / Desenho de Equipamento / Sistemas Microeletromecânicos Limite: Humanos Idioma: Chinês Revista: Journal of Biomedical Engineering Ano de publicação: 2005 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Bombas de Infusão Implantáveis / Sistemas de Liberação de Medicamentos / Desenho de Equipamento / Sistemas Microeletromecânicos Limite: Humanos Idioma: Chinês Revista: Journal of Biomedical Engineering Ano de publicação: 2005 Tipo de documento: Artigo