Cytotoxicity study of heparin coated polyvinyl chloride material / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 739-741, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-238352
ABSTRACT
In this study, heparin ionically coated polyvinyl chloride (PVC) material was prepared by heparin-benzalkonium chloride complex (Group A), heparin-benzalkonium bromide complex (Group B) and heparin-polyethyleneimine compound (Group C). Cytotoxicity evaluation was conducted by direct cell contact evaluation and MTT colorimetry method. The results showed Group A and Group B caused L-929 cells to die out while Group C showed good compatibility with cells. The OD levels of Group A and B were lower than that of the Group C in MTT test. Method A and method B of heparin coating had remarkable cytotoxicity, while method C had little cytotoxicity and could be further studied for clinical use.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Cloreto de Polivinila
/
Teste de Materiais
/
Heparina
/
Células Cultivadas
/
Materiais Revestidos Biocompatíveis
/
Biologia Celular
/
Toxicidade
/
Fibroblastos
Limite:
Animais
Idioma:
Chinês
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2005
Tipo de documento:
Artigo
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