Molecular genetics of globozoospermia: an update / 中华男科学杂志
National Journal of Andrology
; (12): 935-938, 2011.
Article
em Zh
| WPRIM
| ID: wpr-239054
Biblioteca responsável:
WPRO
ABSTRACT
Globozoospermia, as a severe teratozoospermia caused by gene mutations, is a rare congenital disease with main clinical manifestations of the round head of sperm and abnormality or absence of acrosome, and its precise mechanism is not yet clear. Studies show that the pathogenic genes associated with globozoospermia include SPATA16, PICK1, GOPC, Hrb, Csnk2a2 and bs. This paper outlines the progress in the studies of molecular genetics of globozoospermia, aiming to contribute to the molecular diagnosis and mechanism investigation of the disease.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Patologia
/
Espermatozoides
/
Anormalidades Congênitas
/
Acrossomo
/
Genética
/
Infertilidade Masculina
/
Mutação
Limite:
Humans
/
Male
Idioma:
Zh
Revista:
National Journal of Andrology
Ano de publicação:
2011
Tipo de documento:
Article