Current advances in diagnostic methods of Acanthamoeba keratitis / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 3165-3170, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-240210
ABSTRACT
<p><b>OBJECTIVE</b>The objective of this article was to review the current advances in diagnostic methods for Acanthamoeba keratitis (AK).</p><p><b>DATA SOURCES</b>Data used in this review were retrieved from PubMed (1970-2013). The terms "Acanthamoeba keratitis" and "diagnosis" were used for the literature search.</p><p><b>STUDY SELECTION</b>Data from published articles regarding AK and diagnosis in clinical trials were identified and reviewed.</p><p><b>RESULTS</b>The diagnostic methods for the eight species implicated in AK were reviewed. Among all diagnostic procedures, corneal scraping and smear examination was an essential diagnostic method. Polymerase chain reaction was the most sensitive and accurate detection method. Culturing of Acanthamoeba was a reliable method for final diagnosis of AK. Confocal microscopy to detect Acanthamoeba was also effective, without any invasive procedure, and was helpful in the early diagnosis of AK.</p><p><b>CONCLUSION</b>Clinically, conjunction of various diagnostic methods to diagnose AK was necessary.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Acuidade Visual
/
Ceratite por Acanthamoeba
/
Diagnóstico
Tipo de estudo:
Estudo diagnóstico
/
Estudo de rastreamento
Limite:
Humanos
Idioma:
Inglês
Revista:
Chinese Medical Journal
Ano de publicação:
2014
Tipo de documento:
Artigo
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