Effect of astragalus injection combined with chemotherapy on quality of life in patients with advanced non-small cell lung cancer / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 733-735, 2003.
Article
em Zh
| WPRIM
| ID: wpr-240875
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To observe the effect of Astragalus injection (AI) combined with chemotherapy on quality of life (QOF) in patients with advanced non-small cell lung caner (NSCLC).</p><p><b>METHODS</b>Sixty-NSCLC patients were randomly divided into the treated group (n = 30, treated with AI combined with chemotherapy) and the control group (n = 30, treated with chemotherapy alone). Chemotherapy of MVP protocol was applied to both groups. AI was supplemented to the treated group by intravenous dripping 60 ml per day. Treatment of 21-28 days as one treatment cycle, and 2-3 treatment cycles were applied.</p><p><b>RESULTS</b>The effective rate in the treated group was 40.0% and in the control group was 36.7%, the mean remission rate in the treated and control group was 5.4 months and 3.3 months, the median survival period 11 months and 7 months, and the 1-year survival rate 46.75% and 30.0%, respectively, the differences of these indexes between the two groups were all significant (P < 0.05). Moreover, the clinical improving rate and QOF elevation rate in the treated group was 80.4% and 43.3%, as compared with those in the control group (50.0% and 23.3% respectively), the difference was also significant (P < 0.01).</p><p><b>CONCLUSION</b>AI combined with chemotherapy can significantly improve the QOF in NSCLC patients of advanced stage.</p>
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Índice:
WPRIM
Assunto principal:
Qualidade de Vida
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Vimblastina
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Medicamentos de Ervas Chinesas
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Carcinoma de Células Escamosas
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Protocolos de Quimioterapia Combinada Antineoplásica
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Cisplatino
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Carcinoma Pulmonar de Células não Pequenas
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Astragalus propinquus
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Usos Terapêuticos
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Tratamento Farmacológico
Tipo de estudo:
Guideline
Limite:
Adult
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Aged
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Chinese Journal of Integrated Traditional and Western Medicine
Ano de publicação:
2003
Tipo de documento:
Article