Hemophilia B replacement therapy drugs / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 164-171, 2016.
Artigo
em Chinês
| WPRIM
| ID: wpr-242304
ABSTRACT
Hemophilia B is an X chromosome linked hereditary hemorrhagic disease, which is caused by the lose function mutation of factor IX (FIX), and significantly affects the patients' lifespan and life quality. The severity of hemophilia B depends on the FIX level in the plasma. By referring to the relevant literatures, we reviewed and summarized hemophilia B replacement therapies. Specifically, we focus on recombinant factor IX products on the market and those in the pipeline, especially on the long-acting factor IX drugs, to provide the basis for researches of new hemophilia B drugs.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Proteínas Recombinantes
/
Fator IX
/
Hemofilia B
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Genética
/
Mutação
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Biotechnology
Ano de publicação:
2016
Tipo de documento:
Artigo
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