CRISPR-Cas9 mediated genome editing in Caenorhabditis elegans / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 1693-1699, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-243679
ABSTRACT
The development of genome editing techniques based on CRISPR (Clustered regularly interspaced short palindromic repeats)-Cas9 system has revolutionized biomedical researches. It can be utilized to edit genome sequence in almost any organisms including Caenorhabditis elegans, one of the most convenient and classic genetic model animals. The application of CRISPR-Cas9 mediated genome editing in C. elegans promotes the functional analysis of gene and proteins under many physiological conditions. In this mini-review, we summarized the development of CRISPR-Cas9-based genome editing in C. elegans.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Biotechnology
Ano de publicação:
2017
Tipo de documento:
Artigo
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