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Natural killer-like T-cell lymphoma/leukemia--a case report and literature review / 中华血液学杂志
Chinese Journal of Hematology ; (12): 226-230, 2006.
Artigo em Chinês | WPRIM | ID: wpr-243969
ABSTRACT
<p><b>OBJECTIVE</b>To identify the clinical and pathological features of natural killer-like T-cell lymphoma/leukemia.</p><p><b>METHODS</b>The characteristics of natural killer-like T-cell lymphoma/leukemia was discussed with report a new case and review of literatures.</p><p><b>RESULTS</b>A 16-year-old girl was referred to our hospital because of fever and disseminated cutaneous herpes and ulcer. Atypical lymphoid cells surrounded the dermal vessels with a CD3(+), CD8(+), CD4(-), CD5(-), CD10(-), CD19(-), CD57(-), CD56(+), perforin(+), granzyme B(+) immunophenotype and rearranged T-cell receptor-gamma gene implicated natural killer-like T cell origin. She was treated with prednisone and for several months. Then the patient developed progressive spleen enlargement with overt leukemia, which led to her eventual death.</p><p><b>CONCLUSIONS</b>Natural killer-like T-cell lymphoma/leukemia is a rare disease with distinctive clinical, histopathologic, and immuno phenotypic characteristics. Current treatment modalities are ineffective for most of the patients.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Patologia / Células Matadoras Naturais / Leucemia de Células T / Linfoma de Células T / Antígeno CD56 / Alergia e Imunologia Tipo de estudo: Estudo prognóstico Limite: Adolescente / Feminino / Humanos Idioma: Chinês Revista: Chinese Journal of Hematology Ano de publicação: 2006 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Patologia / Células Matadoras Naturais / Leucemia de Células T / Linfoma de Células T / Antígeno CD56 / Alergia e Imunologia Tipo de estudo: Estudo prognóstico Limite: Adolescente / Feminino / Humanos Idioma: Chinês Revista: Chinese Journal of Hematology Ano de publicação: 2006 Tipo de documento: Artigo