Studies on release behavior of sustained release tablets of extracts of Gardenia by antioxidant activity / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3274-3277, 2014.
Artigo
em Chinês
| WPRIM
| ID: wpr-244582
ABSTRACT
Using sustained release tablets of gardenia extract as model drug and DPPH radical scavenging capacity as antioxidant index, the feasibility of using pharmacodynamics index was explored to evaluate sustained release tablets. Applying the established quantifiable method of DPPH radical scavenging to the dissolved liquid of model drug, release profiles and biological effects profiles were drawn, and their correlation was discussed. A good correlation was observed by linear regression and f2 actor, suggesting that the indicator could be used to evaluate sustained release tabletsofextracts of gardenia in which iridoids were mainly involved.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Oxirredução
/
Farmacologia
/
Picratos
/
Comprimidos
/
Compostos de Bifenilo
/
Farmacocinética
/
Extratos Vegetais
/
Cinética
/
Modelos Lineares
/
Química
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2014
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS