Key problems in using ultrasonic cavitating bubble as a gene or drug vector / 生物医学工程学杂志

ABSTRACT

Ultrasound, serveing as an oscillating source, can induce cavitation in liquids; and the bubble produced in this process is a very promising kind of vector for gene delivery and drug target release, owing to its unique properties. This article involves the cavitation mechanism, the control over sonoporation, and the influence of ultrasound contrast agent. The status quo of research and the challenges encountered are discussed. This overview is devoted to providing a theoretical basis for clinical use of cavitating bubble vector.