A study of the ultrastructure and gene location of hereditary gingival fibromatosis / 中华口腔医学杂志
Chinese Journal of Stomatology
;
(12): 170-172, 2002.
Artigo
em Inglês
| WPRIM
| ID: wpr-244809
ABSTRACT
<p><b>OBJECTIVE</b>To ascertain histology changes of hereditary gingival fibromatosis (HGF) and the location of HGF gene.</p><p><b>METHODS</b>A pedigree analyses of HGF; and the ultrastructure of gingival overgrowth tissue was observed with electron microscopy. The overgrowth of the HGF gene was defined with microsatellite markers.</p><p><b>RESULTS</b>The connective tissue of HGF consisted of coarse collagen bundles and several kinds of cells arranged abnormally, such as epithelial cells, smooth muscle cells and so on; the HGF locus had been mapped to chromosome 5q13-q22.</p><p><b>CONCLUSIONS</b>The gingival pathologic changes resemble "hamartoma"; the findings has implications for identification of the underlying genetic basis of HGF.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Linhagem
/
Cromossomos Humanos Par 5
/
Microscopia Eletrônica
/
Saúde da Família
/
Mapeamento Cromossômico
/
Repetições de Microssatélites
/
Predisposição Genética para Doença
/
Fibromatose Gengival
/
Genética
Tipo de estudo:
Estudo prognóstico
Limite:
Criança
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Chinese Journal of Stomatology
Ano de publicação:
2002
Tipo de documento:
Artigo
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