Cure effects of Jiangu Fufang on osteoporotic model induced by ovariectomy / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To explore the cure effects of Jiangu Fufang on osteoporotic model induced by ovariectomy.</p><p><b>METHOD</b>Rats were ovariectomized and administered drugs for 3 monthes. Bone mineral density and biomechanics properties, histomorphometric analysis and biochemical index such as calcium, phosphorus, alkaline phosphatase were detected.</p><p><b>RESULT</b>Jiangu Fufang could significantly increase bone density and biomechanics properties. The level of calcium, phosphorus and alkaline phosphatase were restored by Jiangu Fufang. Jiangu Fufang could significantly increase area of bone trabecula, thickness of cortical bone and bone trabecula.</p><p><b>CONCLUSION</b>Jiangu Fufang could cure osteoporosis through increasing bone mineral density, improving bone biomechanics properties, and effecting bone metabolism.</p>