Increase in concentration of soluble HLA-G in high-quality embryos after intracytoplasmic sperm injection / 대한해부학회지
Anatomy & Cell Biology
;
: 331-336, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-24635
ABSTRACT
Non-invasive methods are normally preferred to conventional invasive methods when selecting suitable embryos to improve pregnancy rates after assisted reproduction techniques. One of the most recognized non-invasive methods is to examine the supernatants of embryo culture media. Soluble human leukocyte antigen, class I, G (sHLA-G) antigen is a non-classical class I molecule that has been widely considered as a marker of pregnancy failure or implantation success. In the current study of some Iranian patients, we examined the concentration of sHLA-G at different time points after intracytoplasmic sperm injection and compared the rates to the morphology and quality of the selected embryos. We showed that the concentration of sHLA-G increases over time in high-quality embryos. We conclude that there is a positive relationship between morphology, quality, and sHLA-G concentration. We suggest that this relationship can be used to increase the chance of a successful pregnancy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Técnicas Reprodutivas
/
Taxa de Gravidez
/
Injeções de Esperma Intracitoplásmicas
/
Meios de Cultura
/
Técnicas de Reprodução Assistida
/
Estruturas Embrionárias
/
Antígenos HLA-G
/
Leucócitos
Limite:
Humanos
/
Gravidez
Idioma:
Inglês
Revista:
Anatomy & Cell Biology
Ano de publicação:
2011
Tipo de documento:
Artigo
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