Risk factors analysis of nonalcoholic fatty liver disease in Chinese men / 中华肝脏病杂志
Chinese Journal of Hepatology
; (12): 62-65, 2013.
Article
em Zh
| WPRIM
| ID: wpr-246741
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore risk factors of nonalcoholic fatty liver disease (NAFLD) in men in order to provide a theoretical basis for developing more effective NAFLD prevention and control strategies.</p><p><b>METHODS</b>One-hundred-and-two male patients (37.3+/-11.4 years old) hospitalized with NAFLD at the Dongnan Affiliated Hospital of Xiamen University between January 2009 and December 2010 were enrolled in the study, along with 23 age-matched healthy men (34.4+/-16.7 years old) to serve as the control group. The correlation(s) of body mass index (BMI; overweight defined as more than or equal to 22.717 kg/m2), waist circumference (WC), waist-to-hip ratio (WHR; central obesity defined as more than or equal to 0.866), fasting plasma glucose (FPG), triglyceride (TG), and total cholesterol (TC) with NAFLD was analyzed by univariate and multivariate logistic regression analyses. Receiver operating characteristic (ROC) curves were used to select proper thresholds for classification.</p><p><b>RESULTS</b>BMI, WC, WHR, FPG, TG, and TC were significantly different between the cases and controls (P less than 0.01). BMI, WC, WHR, TG and TC were identified as risk factors of NAFLD in these male cases (P less than 0.01). Relative to WC, TG and TC, both BMI and WHR had significant predictive value for NAFLD (odds ratio (OR) = 10.819 and 10.588, respectively). In addition, BMI had the highest diagnostic value for the prediction of NAFLD (area under the curve (AUC) = 0.931) followed by WHR (AUC = 0.879).</p><p><b>CONCLUSION</b>BMI, WC, WHR, TG, and TC are risk factors of NAFLD in Chinese men. BMI and WHR are effective anthroposomatology indices of NAFLD and may be useful factors on which to base future prevention and early diagnosis strategies for NAFLD in males.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Índice de Massa Corporal
/
Fatores de Risco
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Relação Cintura-Quadril
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Circunferência da Cintura
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Hepatopatia Gordurosa não Alcoólica
Tipo de estudo:
Etiology_studies
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Prognostic_studies
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Risk_factors_studies
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Screening_studies
Limite:
Humans
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Male
Idioma:
Zh
Revista:
Chinese Journal of Hepatology
Ano de publicação:
2013
Tipo de documento:
Article