Serological Characteristics and Family Survey of 3 Cases of H-deficient Blood Group / 中国实验血液学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the serological characteristics and the genetic status of the family of H-deficient blood group in Jining area of Shandong province in China.</p><p><b>METHODS</b>ABO, H, and Lewis blood groups in 3 probands were screened out by the serological method, and saliva testing was performed on all the individuals. The presence of weak A or B on the RBC was confirmed by using the adsorption-elution procedure.</p><p><b>RESULTS</b>Three cases of H-deficient blood group were identified to be para-Bombay blood group (secretor), out of 3 cases, 2 cases were Bh, 1 case was Ah, and anti-H or anti-HI antibody was detected in their serum.</p><p><b>CONCLUSION</b>Three cases of H-deficerent blood group are para-Bombay phenotype, among them one proband's parents have been confirmed to be consanguineous relationship.</p>