Determination of evodiamine and rutacarpine in zhuyu hewei zhitong capsules by HPLC / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 871-873, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-247370
ABSTRACT
<p><b>OBJECTIVE</b>To develop a HPLC method for the determination of evodiamine and rutacarpine in Zhuyu Hewei Zhitong capsules.</p><p><b>METHOD</b>The separation was performed at 30 degrees C on an Eclipse XDB-C18 column (4.6 mm x 150 mm, 5 microm) eluted with the mobile phase consisted of acetonitrile-water(4555). The detection wavelength was 250 nm.</p><p><b>RESULTS</b>The standard curve for evodiamine is linear in the range of 0.0510-0.560 microg, the average recovery was 97.5% (RSD 1.0%). The standard curve for rutacarpine is linear in the range of 0.0508-0.559 microg, the average recovery was 98.7% (RSD 1.5%).</p><p><b>CONCLUSION</b>The method is specific, accurate and stable. It can be used for detemination of evodiamine and rutacarpine in Zhuyu Hewei Zhitong capsules.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Controle de Qualidade
/
Quinazolinas
/
Padrões de Referência
/
Cápsulas
/
Medicamentos de Ervas Chinesas
/
Modelos Lineares
/
Química
/
Reprodutibilidade dos Testes
/
Cromatografia Líquida de Alta Pressão
/
Alcaloides
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2011
Tipo de documento:
Artigo
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