Metabolism of mangiferin by human intestinal bacteria in vitro / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 443-445, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-247462
ABSTRACT
<p><b>OBJECTIVE</b>To study the metabolism of mangiferin by human intestinal bacteria in vitro.</p><p><b>METHOD</b>Human intestinal bacteria and mangiferin were incubated under anaerobic conditions in vitro. The metabolite was separated and purified by D101 macroporous resin column and preparation high performance liquid chromatography, and its structure was identified by MS and NMR.</p><p><b>RESULT</b>After 12 h incubation with human intestinal bacteria, the content of mangiferin metabolite reached the maximum, and it was determined as 1, 3, 6, 7-tetrahydroxyxanthen by MS and NMR.</p><p><b>CONCLUSION</b>Mangiferin can be metabolized in vitro by human intestinal bacteria into its aglycone (1, 3, 6, 7-tetrahydroxyxanthen).</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Bactérias
/
Cromatografia Líquida de Alta Pressão
/
Xantonas
/
Intestinos
/
Metabolismo
/
Microbiologia
Limite:
Humanos
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2011
Tipo de documento:
Artigo
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