Prognostic Impact of Cerebral Small Vessel Disease on Stroke Outcome / 대한뇌졸중학회지
Journal of Stroke
;
: 101-110, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-24751
ABSTRACT
Cerebral small vessel disease (SVD), which includes white matter hyperintensities (WMHs), silent brain infarction (SBI), and cerebral microbleeds (CMBs), develops in a conjunction of cumulated injuries to cerebral microvascular beds, increased permeability of blood-brain barriers, and chronic oligemia. SVD is easily detected by routine neuroimaging modalities such as brain computed tomography or magnetic resonance imaging. Research has revealed that the presence of SVD markers may increase the risk of future vascular events as well as deteriorate functional recovery and neurocognitive trajectories after stroke, and such an association could also be applied to hemorrhagic stroke survivors. Currently, the specific mechanistic processes leading to the development and manifestation of SVD risk factors are unknown, and further studies with novel methodological tools are warranted. In this review, recent studies regarding the prognostic impact of WMHs, SBI, and CMBs on stroke survivors and briefly summarize the pathophysiological concepts underlying the manifestation of cerebral SVD.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Permeabilidade
/
Prognóstico
/
Encéfalo
/
Imageamento por Ressonância Magnética
/
Barreira Hematoencefálica
/
Fatores de Risco
/
Sobreviventes
/
Acidente Vascular Cerebral
/
Infarto Encefálico
/
Doenças de Pequenos Vasos Cerebrais
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Journal of Stroke
Ano de publicação:
2015
Tipo de documento:
Artigo
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