Comparison of the cardioprotection between crystalloid and blood cardioplegia in adult patients undergoing cardiac surgery: a meta-analysis / 中华外科杂志
Chinese Journal of Surgery
;
(12): 71-76, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-247887
ABSTRACT
<p><b>OBJECTIVES</b>To compare the cardioprotection effect between blood and crystalloid cardioplegia during cardiac surgery in adult patients, and provide a theoretical basis for optimal myocardial protection strategies.</p><p><b>METHODS</b>A meta-analysis of randomized controlled trials (RCT) studies about comparing blood and crystalloid cardioplegia in adult patients undergoing cardiac surgery were performed. Cochrane library (Issue 3, 2011), MEDLINE, EMBase, PubMed, HighWire, CBM and CNKI were searched from January 1985 to December 2011. Studies were assessed according to the Cochrane Handbook for systematic reviews. Data were extracted from these trials and analyzed by RevMan5.1 software.</p><p><b>RESULTS</b>Sixteen trials involved 3934 patients were included, 2004 cases were in blood group, and 1930 were in crystalloid group. There was no statistical heterogeneity between studies using a fixed effects model. Meta-analysis indicated that, there were no significant differences between blood and crystalloid group in the incidence of postoperative 30 days mortality (OR = 1.11, 95%CI 0.59 - 2.08, P = 0.74), the incidence of postoperative low cardiac output (OR = 0.98, 95%CI 0.41 - 2.33, P = 0.85), the incidence of perioperative myocardial infarctions (OR = 0.85, 95%CI 0.55 - 1.29, P = 0.44), and inotropic support requirement (OR = 1.05, 95%CI 0.81 - 1.38, P = 0.70).</p><p><b>CONCLUSION</b>The blood cardioplegia is no difference with crystalloid cardioplegia in adult patients undergoing cardiac surgery.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Complicações Pós-Operatórias
/
Soluções Cardioplégicas
/
Ensaios Clínicos Controlados Aleatórios como Assunto
/
Epidemiologia
/
Procedimentos Cirúrgicos Cardíacos
/
Soluções Isotônicas
Tipo de estudo:
Ensaio Clínico Controlado
/
Revisões Sistemáticas Avaliadas
Limite:
Adulto
/
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Surgery
Ano de publicação:
2013
Tipo de documento:
Artigo
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