Researches on the polymorphism of cytochrome P450 2A6 / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 424-427, 2002.
Artigo
em Chinês
| WPRIM
| ID: wpr-248531
ABSTRACT
Cytochrome P450 2A6(CYP2A6) is known as a major enzyme responsible for C-oxidation of nicotine and 7-hydroxylation of coumarin. The article reviews different alleles of CYP2A6 that have been discovered, their effect on CYP 2A6 activity and the relationship between genetic polymorphism of CYP2A6 and smoking behavior as well as susceptibility of lung and esophageal cancer in different individuals.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Polimorfismo Genético
/
Pesquisa
/
Neoplasias Esofágicas
/
Hidrocarboneto de Aril Hidroxilases
/
Fumar
/
Predisposição Genética para Doença
/
Citocromo P-450 CYP2A6
/
Genética
/
Oxigenases de Função Mista
/
Neoplasias Pulmonares
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Medical Genetics
Ano de publicação:
2002
Tipo de documento:
Artigo
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