To explore the clinical significance of HBV large protein (HBV-LP) in diagnosing viral replication / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 380-382, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-248746
ABSTRACT
<p><b>OBJECTIVE</b>To explore the clinical significance of HBV large protein (HBV-LP) in diagnosing viral replication, we detected the HBV-LP, HBV DNA and the hepatitis B viral markers (HBV M) in the serum of the patients infected with HBV.</p><p><b>METHODS</b>HBV-LP and HBV M were analyzed by using ELISA. HBV-DNA was quantitatively detected using real-time fluorescent polymerase chain reaction.</p><p><b>RESULTS</b>(1) No significant difference between the detectable rate of HBV DNA and HBV-LP was found in the same HBV M (P 0.05). (2) No significant difference between the positive rate of HBV DNA and HBV-LP was found in HBeAg negative patients. (3) The contents of serum HBV-LP was positively correlated with the number of HBV DNA copies.</p><p><b>CONCLUSION</b>There was a close correlation between the positive rate of HBV-LP and HBV DNA, and HBV-LP is a reliable serological marker that can reflect the replication of HBV.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Replicação Viral
/
Sangue
/
DNA Viral
/
Vírus da Hepatite B
/
Antígenos E da Hepatite B
/
Antígenos de Superfície da Hepatite B
Limite:
Adolescente
/
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Experimental and Clinical Virology
Ano de publicação:
2007
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS