Effects of Kang Gang Qian Granule (KGQG) on clinical and pathological features in chronic hepatitis B patients / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 369-371, 2007.
Article
em Zh
| WPRIM
| ID: wpr-248750
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore the efficacy of KGQG and its therapeutic mechanisms in chronic hepatitis B patients with liver fibrosis.</p><p><b>METHODS</b>57 chronic hepatitis B patients with liver fibrosis were randomly divided into two groups: 45 cases in KGQG group were treated by KGQG and routine medications; 12 cases in control group were treated by routine medications only. Serum liver function test results, PCIII, CIV, HA and liver biopsy results of these 57 patients were simultaneously collected and analyzed before and after this intervention.</p><p><b>RESULTS</b>KGQG group showed better efficacy over control group in liver function recovery, decrease of serum PCIII, CIV, HA levels and liver pathologic grades (P 0.05 or 0.01).</p><p><b>CONCLUSION</b>The KGQG could effectively ameliorate liver function and facilitate the inhibition and degradation of liver fibrosis in chronic hepatitis B patients, which may be developed as a novel therapeusis to treat this hard-to-cure disease.</p>
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Índice:
WPRIM
Assunto principal:
Patologia
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Medicamentos de Ervas Chinesas
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Imuno-Histoquímica
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Hepatite B Crônica
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Colágeno Tipo IV
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Usos Terapêuticos
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Tratamento Farmacológico
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Cirrose Hepática
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Medicina Tradicional Chinesa
Tipo de estudo:
Diagnostic_studies
Limite:
Adolescent
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Adult
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Chinese Journal of Experimental and Clinical Virology
Ano de publicação:
2007
Tipo de documento:
Article