Variations of hepatitis B virus infection epidemic pattern after long-term HBV vaccine immunization / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 253-255, 2007.
Article
em Zh
| WPRIM
| ID: wpr-248787
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the epidemic pattern and trend of HBV infection in the area where the people had been immunized by HBV vaccine for 20 years.</p><p><b>METHODS</b>The whole sampling method was applied in combination with cross-sectional investigation. Blood samples were taken from every member of families. Markers of HBV infection were determined by using solid-phase radioimmunoassay (SPRIA).</p><p><b>RESULTS</b>(1) The average HBsAg positive rate was 7.5%. The positive rate of markers for HBV infection of 0-19 years old subjects were lower than those of > or = 20 years old subjects. (2) The positive rate of HBsAg of 0-19 years old subjects in 1985 was higher than that in 2005. The anti-HBs positive rate in 1985 stemmed to be higher with age. It was 12.4% in 1- age group to 53.8% in >60 years age group. While the result of 2005 showed that the anti-HBs positive rate of 0-19 years old subjects dropped with age. The anti-HBc positive rate in 1985 also tended to be higher with age. But the result of 2005 showed that the rate of 0-19 years old subjects was just 1.4% to 16.8%.</p><p><b>CONCLUSION</b>The epidemic patterns of HBV infection have had significant variations in the target population. HBV vaccine immunization has obtained excellent efficacy.</p>
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Índice:
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Assunto principal:
Fatores de Tempo
/
Sangue
/
Estudos Soroepidemiológicos
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China
/
Epidemiologia
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Estudos Transversais
/
Imunização
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Resultado do Tratamento
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Vacinas contra Hepatite B
/
Usos Terapêuticos
Tipo de estudo:
Observational_studies
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Prevalence_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
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Newborn
País/Região como assunto:
Asia
Idioma:
Zh
Revista:
Chinese Journal of Experimental and Clinical Virology
Ano de publicação:
2007
Tipo de documento:
Article