Role of Wnt/β-catenin signaling pathway in promoting tumorigenesis of hepatocellular carcinoma / 南方医科大学学报
Journal of Southern Medical University
;
(12): 913-917, 2014.
Artigo
em Chinês
| WPRIM
| ID: wpr-249333
ABSTRACT
Wnt/β-catenin signaling pathway has a close relationship with cancer and is abnormally activated in many human cancers. Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death worldwide, but the molecular mechanisms of HCC are still poorly understood. Current studies indicate that Wnt/β-catenin signaling pathway plays a key role in the development and progression of HCC. Validating the role and mechanism of Wnt/β-catenin signaling pathway in HCC will provide a theoretical basis for early diagnosis and treatment of HCC. In this review, we summarize the role of Wnt/β-catenin signaling pathway in HCC and the progress of current researches.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Carcinoma Hepatocelular
/
Proteínas Wnt
/
Beta Catenina
/
Via de Sinalização Wnt
/
Carcinogênese
/
Neoplasias Hepáticas
Tipo de estudo:
Estudo de rastreamento
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2014
Tipo de documento:
Artigo
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