Evaluation of a heart-type fatty acid-binding protein detection kit for diagnosis of acute coronary syndrome / 南方医科大学学报
Journal of Southern Medical University
;
(12): 901-903, 2014.
Artigo
em Chinês
| WPRIM
| ID: wpr-249336
ABSTRACT
<p><b>OBJECTIVE</b>To evaluation the performance of a heart-type fatty acid-binding protein (H-FABP) ELISA detection kit in the clinical diagnosis of acute coronary syndrome (ACS).</p><p><b>METHODS</b>Plasma or serum samples from 160 suspected ACS patients hospitalized in General Hospital of PLA were examined using Lanzhou H-FABP reagent kit and Holland H-FABP kit. Correlation of the two kits was evaluated and Kappa test was used to examine the consistency of the results of the two products.</p><p><b>RESULTS</b>The sensitivity of H-FABP diagnosis of ACS detection Lanzhou kit was 91.8%, the specificity was 88.7%, and the total diagnostic rate was 90.42%. The sensitivity of H-FABP diagnosis of ACS detection Holland kit was 90.3%, the specificity was 86.8%, and the total diagnostic rate was 88.75%. The test results showed that two products yielded comparable results (P=0.668, >0.05) with a good consistency (Kappa=0.726, P<0.01).</p><p><b>CONCLUSIONS</b>H-FABP ELISA detection kit produccted by LanZhou biological research institute has a good correlation with H-FABP detection kit produced by HBT company of Holland and has the potential for clinical application.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Kit de Reagentes para Diagnóstico
/
Sangue
/
Ensaio de Imunoadsorção Enzimática
/
Biomarcadores
/
Reprodutibilidade dos Testes
/
Sensibilidade e Especificidade
/
Diagnóstico
/
Proteínas de Ligação a Ácido Graxo
/
Síndrome Coronariana Aguda
/
Proteína 3 Ligante de Ácido Graxo
Tipo de estudo:
Estudo diagnóstico
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2014
Tipo de documento:
Artigo
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