The advance and limitation of microencapsulated grafts transplantation / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 678-683, 2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-249530
ABSTRACT
Microencapsulation of cells or tissue fragments represents a potentially effective method to prevent graft rejection in allotransplantation and xenotransplantation without the need of immunosuppression, but the functional survival of all trial grafts is still limited. Usually, graft failure is mainly interpreted as the consequence of the progressive fibrotic overgrowth of capsules, the insufficient supply of oxygen and nutrition to the encapsulated graft, and the dysfunction of the encapsulated graft induced by small proinflammatory factors. These detrimental factors are interrelatd with the microcapsules, the implanted graft, and the transplantation site. This article reviews and summarizes the advance and the limitation of microencapsulated grafts transplantation in the above-mentioned aspects.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Transplante Heterólogo
/
Materiais Biocompatíveis
/
Cápsulas
/
Química
/
Transplante das Ilhotas Pancreáticas
/
Alginatos
/
Alergia e Imunologia
/
Sobrevivência de Enxerto
/
Métodos
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2006
Tipo de documento:
Artigo
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