The unwelcome visitor
Singapore medical journal
;
: 508-quiz 512, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-249691
ABSTRACT
Gout is a chronic, progressive inflammatory disease with intermittent arthritic flares, which should not be regarded as a minor inconvenience or nuisance. It can be effectively controlled when the patient's serum urate level is reduced to less than 360 μmol/l (6 mg/dL) by consistent use of urate-lowering pharmacotherapy. Colchicine prophylaxis for gouty flares during titration of urate-lowering therapy has been underused. Holistic long-term management of gout must encompass patient education, evidence-based dietary advice, screening and aggressive treatment of comorbidities such as hypertension, diabetes mellitus, dyslipidaemia and renal impairment. Acute therapies for recurrent attacks with non-steroidal anti-inflammatory drugs, colchicine and/or corticosteroids should be used judiciously, especially in the elderly, due to the risk of toxicities. With appreciation of the underlying pathogenesis and artful use of the limited drug options, control of gout can be effectively achieved, bringing tremendous satisfaction to the patient and doctor.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ácido Úrico
/
Sangue
/
Anti-Inflamatórios não Esteroides
/
Colchicina
/
Doença Crônica
/
Corticosteroides
/
Usos Terapêuticos
/
Diagnóstico
/
Dietoterapia
/
Tratamento Farmacológico
Tipo de estudo:
Estudo diagnóstico
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Singapore medical journal
Ano de publicação:
2012
Tipo de documento:
Artigo
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