Your browser doesn't support javascript.
loading
Effects of programmed cell death on human dental follicle cells and changes of programmed cell death under different hydrostatic pressures / 华西口腔医学杂志
West China Journal of Stomatology ; (6): 466-468, 2006.
Artigo em Chinês | WPRIM | ID: wpr-249792
ABSTRACT
<p><b>OBJECTIVE</b>Tooth eruption requires the presence of the dental follicle (DF) around the unerupted tooth. This study is to investigate programmed cell death on human dental follicle cells and changes of programmed cell death under different hydrostatic pressures 0, 50 and 100 kPa.</p><p><b>METHODS</b>Human dental follicles from third mandibular molars were surgically removed from adolescents who need for orthodontics treatment after informed content, then trypsinized and cultured. Human dental follicle cells were divided into three groups according to different hydrostatic pressures 0, 50 and 100 kPa and their programmed cell death were labeled by using TdT-medi-ated-dUTP nick and labeling (TUNEL).</p><p><b>RESULTS</b>Dental follicle cells cultured were elongate shape and exhibited fibroblastic characteristics. Compared with 0 kPa, programmed cell death cells on human dental follicle cells were increased 0.23% and 31.65% under 50 kPa and 100 kPa hydrostatic pressures respectively. 100 kPa group increased significantly (P < 0.01).</p><p><b>CONCLUSION</b>It suggested that programmed cell death occured in human dental follicle cells cultured in vitro and was influenced by different hydrostatic pressures. Hydrostatic pressure may improve tooth erup-tion through dental follicle.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Erupção Dentária / Apoptose / Saco Dentário / Fibroblastos / Pressão Hidrostática / Dente Molar Limite: Adolescente / Humanos Idioma: Chinês Revista: West China Journal of Stomatology Ano de publicação: 2006 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Erupção Dentária / Apoptose / Saco Dentário / Fibroblastos / Pressão Hidrostática / Dente Molar Limite: Adolescente / Humanos Idioma: Chinês Revista: West China Journal of Stomatology Ano de publicação: 2006 Tipo de documento: Artigo