Evaluation of Osseointegration in Dense Ceramics Using Rabbit's External Fixation Model / 대한정형외과연구학회지
Journal of Korean Orthopaedic Research Society
;
: 151-162, 2003.
Artigo
em Coreano
| WPRIM
| ID: wpr-24987
ABSTRACT
PURPOSE:
To evaluate the osseointegration of different dense ceramics. MATERIALS ANDMETHODS:
Twenty-eight New Zealand white male rabbits were divided into 4 groups by implant materials Cerabone(R)-AW, CaO-SiO2- B2O3 glass ceramics (CS10B), CaO-SiO2- B2O3 glass (CS5B glass) and Cerabone(R)- A W + A l2O3 glass ceramics. We implanted the dense ceramics into the tibia of rabbits with external fixator and checked the radiographs every 4 weeks. The union rate, histology and SEM were evaluated 8 weeks after surgery.RESULTS:
The union rates were 85.7% (6 of 7) in Cerabone(R)-AW, 85.7% (6 of 7) in CS10B, 71.4% (5 of 7) in CS5B glass and 28.6% (2 of 7) in Cerabone(R)-AW+Al2O3 by simple radiographs. The union rates of Cerabone (R)-AW and CS10B were statistically higher than that of Cerabone(R)-AW+Al2O3 (p=0.031). Histologically, the Cerabone(R)-AW had fused with tibia without biodegradation, CS10B, CS5B glass had fused with tibia in some portion but resorbed in others. Cerabone(R)-AW+Al2O3 had not fused with bony tissue.CONCLUSION:
We confirmed the osseointegration and insolubility of Cerabone(R)-AW. We also confirmed the osseointegration and partial solubility of CaO-SiO2-B2O3 glass ceramics. These findings suggest that Cerabone (R)-AW can be used as an insoluble artificial bone and CaO-SiO2-B2O3 glass ceramics as biodegradable bone replacement materials.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Solubilidade
/
Tíbia
/
Cerâmica
/
Fixadores Externos
/
Osseointegração
/
Substitutos Ósseos
/
Vidro
/
Nova Zelândia
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
/
Humanos
/
Masculino
País/Região como assunto:
Oceania
Idioma:
Coreano
Revista:
Journal of Korean Orthopaedic Research Society
Ano de publicação:
2003
Tipo de documento:
Artigo
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