Clinical study on intrauterine hemorrhagic fever with renal syndrome virus infection / 中华实验和临床病毒学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To find out the status of intrauterine infection with hemorrhagic fever with renal syndrome virus (HFRSV).</p><p><b>METHODS</b>The blood of mothers and the umbilical cords were examined by using anti-HFRSV-IgG at labor of mothers infected with HFRSV. The venous blood of naturally delivered babies were examined for anti-HFRSV-Ig M, HI test was used to type the HFRSV.</p><p><b>RESULTS</b>Mothers blood showed positive reaction for anti-HFRSV-IgG. Twenty-three of 27 cases of the fetal death were umbilical cords blood positive two out of twelve of umbilical cord blood that the babies were born naturally after their mothers recovered showed positive for anti-HFRSV -IgG but negative for anti-HFRSV-IgM, 14 babies born naturally normally.</p><p><b>CONCLUSIONS</b>HFRSV can cause intrauterine infection, and lead to fetal death, but no post natal deformity was observed in the babies born naturally.</p>