Advances in the study of the anti-tumor activity of small molecule vascular disrupting agents / 药学学报
Acta Pharmaceutica Sinica
;
(12): 283-288, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-250590
ABSTRACT
Vascular disrupting agents (VDAs) have presented a new kind of anti-cancer drug in recent years. VDAs take advantage of the weakness of established tumor endothelial cells and their supporting structures. In contrast to anti-angiogenic therapy, which inhibits the outgrowth of new blood vessels, vascular targeting treatments selectively attack the existing tumor vasculature. Here we summarized the anti-tumor activities, mechanisms and clinical applications of small molecule VDAs.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Oligopeptídeos
/
Compostos Organofosforados
/
Patologia
/
Farmacologia
/
Serina
/
Estilbenos
/
Bibenzilas
/
Estrutura Molecular
/
Química
/
Difosfatos
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2010
Tipo de documento:
Artigo
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