Network pharmacology: new guidelines for drug discovery / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1472-1477, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-250607
ABSTRACT
The development of new drug is not only the main driving force for the development of pharmaceutical industry, but also plays a very important role in the social development. However, with the increasing demands, new drug development is facing great difficulties in recent years. The hypothesis of highly selective single-target is meeting the challenges because of its limitations. Network pharmacology has been one of the new strategies for new drug discovery based on single-target drug research in recent years. This paper focused on the basis of network pharmacology and its research progress, discussed its development direction and application prospects, and analyzed its limitations and problems as well. The application of network pharmacology in new drug development is discussed by comparing its guidelines with those of traditional Chinese medicine theory and Effective Components Group hypothesis of Chinese medicines.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Algoritmos
/
Software
/
Sistemas de Liberação de Medicamentos
/
Biologia Computacional
/
Biologia de Sistemas
/
Interações Medicamentosas
/
Descoberta de Drogas
/
Medicina Tradicional Chinesa
/
Métodos
Tipo de estudo:
Estudo diagnóstico
/
Guia de Prática Clínica
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2010
Tipo de documento:
Artigo
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