Effect of Candida albicans growth on silicone elastomer containing nano-TiO2 / 中华口腔医学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the antibacterial effect against Candida albicans of the A-2186 silicone elastomer containing nano-TiO2 in vitro.</p><p><b>METHODS</b>Antibacterial agent of nano-TiO2 was added into A-2186 silicone elastomer with incorporating percentages of 0.5%, 1.0%, 1.5%, and 2.0% (W/W). There was no nano-TiO2 in the control group. The antibacterial effect of the A-2186 silicone elastomer was determined using the film contact method with lighting and without lighting.</p><p><b>RESULTS</b>Either with lighting or without lighting, there were significances between the experiment groups and the control group (P < 0.05). When the incorporating percent was 2.0%, the inhibitory effect was the best among the experiment groups. Without lighting, the inhibitory rate was 53.7% and with lighting, the inhibitory rate was 85.9%.</p><p><b>CONCLUSIONS</b>The A-2186 silicone elastomer containing nano-TiO2 has antibacterial properties against Candida albicans, which enhances with increases of nano-TiO2 percent in the material. With the same incorporating percentage, the antibacterial effect with lighting is better than that without lighting.</p>