Two new phenylethanoid glycosides from Corallodiscus flabellata / 药学学报
Acta Pharmaceutica Sinica
; (12): 268-271, 2003.
Article
em Zh
| WPRIM
| ID: wpr-251127
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WPRO
ABSTRACT
<p><b>AIM</b>To study the chemical constituents from Corallodiscus flabellata.</p><p><b>METHODS</b>Fresh plant of Corallodiscus flabellata was extracted twice with boiling water, filtered to remove insoluble materials, concentrated under reduced pressure at temperature 55 degrees C to a small volume. The concentrated liquor was subjected to solvent-solvent partitioning using ether, ethyl acetate, and n-butanol (saturated with water). The fraction of ethyl acetate extract was chromatographed over macroporous adsorption resin (Diaion HP-20) eluted with a mixture of H2O and MeOH in increasing MeOH content. Their fractions from resin were repeatedly chromatographed over Sephadex LH-20, Toyopearl HW-40, gel MCI, Gel CHP-20 and silica gel column. Structures of compounds obtained were identified on the basis of their spectral data, hydrolysis and chemical correlation.</p><p><b>RESULTS</b>Two phenylethanoid glycosides (I, II) and three phenolic acids were obtained from the EtOAc fraction of water-extracts. Their structures were identified as 3,4-dihydroxyphenylethanol-8-O-[beta-D-apiofuranosyl (1-->2)]-beta-D-glucopyranoside (I), 3,4-dihydroxyphenylethanol-8-O-[(5-O- Vanilloyl)-beta-D-apiofuranosyl(1-->2)]-beta-D-glucopyranoside (II), vanillic acid (III), syringic acid (IV) and ferulic acid (V).</p><p><b>CONCLUSION</b>I and II are new compounds. Compounds III, IV and V were isolated from this plant for the first time.</p>
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Assunto principal:
Plantas Medicinais
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Ácido Vanílico
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Medicamentos de Ervas Chinesas
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Estrutura Molecular
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Química
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Magnoliopsida
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Dissacarídeos
Idioma:
Zh
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2003
Tipo de documento:
Article