Interictal epileptiform discharges in children with epilepsy / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 322-324, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-252088
ABSTRACT
<p><b>OBJECTIVE</b>To study the features of interictal epileptiform discharges (IED) during sleep and wakefulness in children with epilepsy.</p><p><b>METHODS</b>The polysomnography, active EEG and video EEG were performed on 48 children with epilepsy during the whole night, and wakefulness of pre- and post-sleep. The epileptiform sharp/spike discharge indexes during sleep and wakefulness were recorded. The positive rate of IED in focal and generalized epilepsy was compared.</p><p><b>RESULTS</b>Of the 48 patients, 25 showed IED, including 9 cases (36.0%) in the generalized seizure group and 16 cases (64.0%) in the focal seizure group (P<0.05). The epileptiform sharp/spike discharge indexes in the whole non-rapid eye movement (NREM) sleep stage (stages S1-S4 21.13+/-19.96, 19.59+/-17.76, 22.85+/-18.99, and 20.37+/-16.63) were significantly higher than that in the wakefulness stage (8.20+/-6.21) (P<0.05). The discharge index in the S3 stage during NREM sleep was higher than that during the rapid eye movement (REM) sleep (22.85+/-18.99 vs 12.91+/-10.95; P<0.05).</p><p><b>CONCLUSIONS</b>The positive rate of IED in the focal seizure group was higher than that in the generalized seizure group. Sleep, especially NREM sleep, facilitates IED in children with epilepsy.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Sono
/
Vigília
/
Polissonografia
/
Eletroencefalografia
/
Epilepsia
Limite:
Criança
/
Criança, pré-escolar
/
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2008
Tipo de documento:
Artigo
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