Progress in TcpC research / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 481-485, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-252602
ABSTRACT
TcpC is a homolog of the Toll/interleukin-1 receptor (TIR) domain and is secreted by uropathogenic E. coli strain CFT073. TcpC can bind to MyD88, hereby exerting inhibitory effects on macrophages. TcpC represents an important virulence factor that promotes bacterial survival and pathogenicity. TcpC plays a critical role in urinary tract infection, particularly in the pathogenesis of pyelonephritis. In this review,the progress and prospects in TcpC research are discussed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Pielonefrite
/
Infecções Urinárias
/
Virulência
/
Proteínas de Escherichia coli
/
Fatores de Virulência
/
Escherichia coli
/
Microbiologia
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Journal of Zhejiang University. Medical sciences
Ano de publicação:
2013
Tipo de documento:
Artigo
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