Epididymal cyst in von Hippel-Lindau syndrome: clinicopathologic analysis of 3 cases / 中华男科学杂志
National Journal of Andrology
;
(12): 142-145, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-252806
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinicopathologic features of epididymal cyst in von Hippel-Lindau (VHL) syndrome.</p><p><b>METHODS</b>We reviewed the clinical data of 3 epididymal cyst patients treated by surgery, and detected the expressions of HIF-1alpha, VEGF, alpha-SMA and CD34 in the epididymal tissue samples by the immunohistochemistry SP method.</p><p><b>RESULTS</b>All the 3 patients underwent surgical removal of the epididymal cyst. Immunohistochemistry of the epididymal tissues showed HIF-1alpha, VEGF, alpha-SMA and CD34 to be positive. All the 3 cases were confirmed to be VHL syndrome, 1 right after surgery, and the other 2 within 8 years postoperatively.</p><p><b>CONCLUSION</b>Epididymal cyst is a usual benign disease, which may occur independently of or be complicated by VHL syndrome. If immunohistochemistry of epididymal tissues shows HIF-1alpha, VEGF, alpha-SMA and CD34 to be positive, VHL syndrome should be considered, and further clinical examinations and post-operation follow-up are necessitated.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Espermatocele
/
Actinas
/
Fator A de Crescimento do Endotélio Vascular
/
Epididimo
/
Subunidade alfa do Fator 1 Induzível por Hipóxia
/
Doença de von Hippel-Lindau
/
Metabolismo
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2010
Tipo de documento:
Artigo
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