The changes and their clinical significance of D-dimer and platelet glycoprotein in patients with coronary heart disease / 中华心血管病杂志
Chinese Journal of Cardiology
;
(12): 724-726, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-253076
ABSTRACT
<p><b>OBJECTIVE</b>To explore the changes and their clinical significance of D-dimer and platelet glycoprotein (GP) in patients with coronary heart disease.</p><p><b>METHODS</b>D-dimer and GP in 20 patients with stable angina (SA group), 48 patients with unstable angina (UA group), and 20 control cases were measured. The changes of D-dimer and GP in patients with and without coronary events were compared. The sensitivity of those changes in the diagnosis of coronary events was evaluated.</p><p><b>RESULTS</b>There were significant differences of D-dimer and GP between UA group and SA group or control group (P < 0.01), while there was no significant difference between SA group and control group (P > 0.05). There were also significant differences of D-dimer and GP between patients with coronary events and patients without coronary events (P < 0.05). In the sensitivity test for detecting coronary events, D-dimer and GPIIb, GPIIIa were much more sensitive than other parameters.</p><p><b>CONCLUSIONS</b>D-dimer and GPIIb, GPIIIa may be regarded as the indexes of coronary thrombosis and used for predicting the severity of coronary events.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Produtos de Degradação da Fibrina e do Fibrinogênio
/
Glicoproteínas da Membrana de Plaquetas
/
Estudos de Casos e Controles
/
Complexo Glicoproteico GPIIb-IIIa de Plaquetas
/
Doença das Coronárias
/
Glicoproteína IIb da Membrana de Plaquetas
/
Diagnóstico
/
Angina Instável
/
Metabolismo
/
Infarto do Miocárdio
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Fatores de risco
Limite:
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Cardiology
Ano de publicação:
2005
Tipo de documento:
Artigo
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