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Plasma suPAR level in patients with multiple myeloma / 中国实验血液学杂志
Journal of Experimental Hematology ; (6): 197-199, 2008.
Artigo em Chinês | WPRIM | ID: wpr-253352
ABSTRACT
To investigate the changes of plasma suPAR level in patients with multiple myeloma, ELISA was used to detect plasma suPAR level, and routine examination was performed for other clinical indexes in 26 multiple myeloma patients. The results showed that plasma suPAR level in patients was 4.31+/-1.67 ng/ml, which was obviously higher than that in control group (1.87+/-0.27 ng/ml) (p<0.01). Plasma suPAR level in IgM subtype patients was 6.18+/-3.61 ng/ml, which was highest among all the subtypes; the plasma suPAR levels in non-secretion subtype, IgG and IgA subtype were 4.43+/-1.55 ng/ml, 4.00+/-0.95 ng/ml and 3.50+/-1.60 ng/ml respectively. The plasma suPAR levels in all subtypes were higher than that in control group, but there was no differences between these subtypes. SuPAR level was correlated with the blood sedimentation rate, creatinine level and hemoglobin level, plasma cell ratio and M protein level. It is concluded that the change of plasma suPAR level in multiple myeloma contributes to predict the development and prognosis of the disease.
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Prognóstico / Solubilidade / Sangue / Ensaio de Imunoadsorção Enzimática / Classificação / Receptores de Ativador de Plasminogênio Tipo Uroquinase / Mieloma Múltiplo Tipo de estudo: Estudo prognóstico Limite: Idoso / Feminino / Humanos / Masculino Idioma: Chinês Revista: Journal of Experimental Hematology Ano de publicação: 2008 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Prognóstico / Solubilidade / Sangue / Ensaio de Imunoadsorção Enzimática / Classificação / Receptores de Ativador de Plasminogênio Tipo Uroquinase / Mieloma Múltiplo Tipo de estudo: Estudo prognóstico Limite: Idoso / Feminino / Humanos / Masculino Idioma: Chinês Revista: Journal of Experimental Hematology Ano de publicação: 2008 Tipo de documento: Artigo