Interaction of metal complexes of bacterial chlorophyll with DNA / 药学学报
Acta Pharmaceutica Sinica
; (12): 1054-1056, 2005.
Article
em Zh
| WPRIM
| ID: wpr-253493
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>AIM</b>Understanding the modes and activities of metal bacterial chlorophylls as PHD sensitizers with DNA.</p><p><b>METHODS</b>The modes and activities of the interaction of DNA and metal complexes of bacterial chlorophyll, which have been prepared by extraction and synthesis reaction, have been discussed according to the ultraviolet-visual spectrum and nucleic acid electrophoresis.</p><p><b>RESULTS</b>It indicates that the system of DNA and metal complexes have enchanced the interaction by the ultraviolet-visual spectrum. At the same time, it also indicates that metal complexes of bacterial chlorophyll and DNA have different combining way and have strong cutting effect in illumination by the nucleic acid electrophoresis.</p><p><b>CONCLUSION</b>This paper proved that metal bacterial chlorophylls as PHD sensitizers have great advantage.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Compostos Organometálicos
/
Farmacologia
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Ligação Proteica
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Espectrofotometria Ultravioleta
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Bacterioclorofilas
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Zinco
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DNA
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Química
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Células HL-60
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Cobre
Limite:
Humans
Idioma:
Zh
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2005
Tipo de documento:
Article