The effect of periodontal initial therapy on circulating TNF-alpha and HbA1C in type 2 diabetes patients with periodontitis / 中华口腔医学杂志
Chinese Journal of Stomatology
;
(12): 364-366, 2003.
Artigo
em Chinês
| WPRIM
| ID: wpr-253696
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effect and mechanism of periodontal initial therapy on type 2 diabetes patients with periodontitis.</p><p><b>METHODS</b>15 type 2 diabetes patients with periodontitis were selected. Their body mass index (BMI), sulcus bleeding index (SBI), probing depth (PD), circulating tumor necrosis factor-alpha (TNF-alpha) concentration, and the value of glycosylated hemoglobin (HbA1C), triglycerides (TG) and cholesterol (CHOL) were assessed respectively before and 4-6 weeks after periodontal initial therapy.</p><p><b>RESULTS</b>After initial therapy, SBI, PD, circulating TNF-alpha concentration, and the value of HbA1C and TG were reduced significantly (P<0.05), while there were no significant differences in BMI and CHOL value (P>0.05).</p><p><b>CONCLUSIONS</b>Periodontal initial therapy can effectively reduce HbA1C value in type 2 diabetes patients with periodontitis, possibly through the reduction of circulating TNF-alpha concentration.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Periodontite
/
Terapêutica
/
Sangue
/
Hemoglobinas Glicadas
/
Índice de Massa Corporal
/
Fator de Necrose Tumoral alfa
/
Diabetes Mellitus Tipo 2
/
Lipídeos
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Stomatology
Ano de publicação:
2003
Tipo de documento:
Artigo
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