Erectile dysfunction in Fragile X patients / 亚洲男科学杂志(英文版)
Asian Journal of Andrology
;
(6): 483-487, 2006.
Artigo
em Inglês
| WPRIM
| ID: wpr-253806
ABSTRACT
<p><b>AIM</b>To report the clinical experience during collecting sperm samples in the Fragile X syndrome (FXS) male patients.</p><p><b>METHODS</b>Two different polymerase chain reaction (PCR) based methods were used for the molecular diagnosis of FXS. Sperm collection was done mostly according to the laboratory manual of the World Health Organization.</p><p><b>RESULTS</b>We failed to collect sperm samples from five Fragile X subjects aged 18-60 years as a result of an unexpected erectile dysfunction (ED). Multiple examinations of the same subject at different times, and of different subjects from different provinces examined by different physicians, showed the same result consistently in all the five subjects.</p><p><b>CONCLUSION</b>Erectile reflex is an instinctive response in all healthy males. The absence of erection can be caused by hormonal, physical or neuronal malfunction. As hormonal profiles were reported to be generally normal in Fragile X men, we propose that an unknown physical factor or the neuronal circuit, or both, underlying the erection is compromised. The finding of this symptom in Fragile X patients may help better understand the clinical spectrum and pathogeneses of the disease.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Linhagem
/
Espermatogênese
/
Sequência de Bases
/
Reação em Cadeia da Polimerase
/
Primers do DNA
/
Síndrome do Cromossomo X Frágil
/
Genética
/
Disfunção Erétil
/
Métodos
Tipo de estudo:
Guia de Prática Clínica
Limite:
Adolescente
/
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Asian Journal of Andrology
Ano de publicação:
2006
Tipo de documento:
Artigo
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