Specific T-cell responses to Mycobacterium tuberculosis protein ESAT-6 in Chinese HIV positive individuals / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 124-126, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-254123
ABSTRACT
<p><b>OBJECTIVE</b>To detect TB specific T cell responses by using the recombinant ESAT-6 protein as stimulus in Chinese HIV infected patients.</p><p><b>METHODS</b>ELISPOT-IFN-gamma assay by using the recombinant ESAT-6 protein as stimulus to detect specific T cell responses in HIV+ patients with or without clinical manifestation of TB diseases.</p><p><b>RESULTS</b>Recombinant ESAT-6 protein specific T cell responses show significant high frequencies in both of TB patients with or without HIV infection than that in the healthy control and HIV+ group without clinical TB diseases.</p><p><b>CONCLUSION</b>The ELISPOT-IFN-gamma assay by using recombinant ESAT-6 protein as stimulus could be used in diagnoses of TB infection in Chinese HIV infected patients.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Proteínas de Bactérias
/
Tuberculose
/
Sangue
/
Proteínas Recombinantes
/
Leucócitos Mononucleares
/
Linfócitos T
/
Infecções por HIV
/
Técnicas Imunoenzimáticas
/
Interferon gama
/
Biologia Celular
Limite:
Adulto
/
Idoso
/
Aged80
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Experimental and Clinical Virology
Ano de publicação:
2008
Tipo de documento:
Artigo
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