Alterations in Hepatic Function after Laparoscopic Assisted Distal Gastrectomy: A Prospective Study
Journal of the Korean Surgical Society
;
: 46-50, 2007.
Artigo
em Coreano
| WPRIM
| ID: wpr-25422
ABSTRACT
PURPOSE:
There is concern about the potential adverse effects on hepatic function due to increased intraabdominal pressure during pneumoperitoneum. The changes in hepatic function following a laparoscopy assisted distal gastrectomy (LADG) and conventional open distal gastrectomy (ODG) for gastric cancer were compared.METHODS:
Between July 2004 and May 2005, 60 patients diagnosed with early gastric cancer at Kangnam St' Mary's hospital; 30 each having undergone LADG and ODG were studied. The levels of alkaline phosphatase (ALP), total bilirubin (TB), aspartate transferase (AST) and alanine transferase (ALT) between the two groups were compared at 24 and 72 hours postoperatively.RESULTS:
The age, sex, body mass index and preoperative hepatic function were not different between the two groups. The operative times were significantly longer in the LADG than the ODG group (298 vs. 184 minutes, P 0.05).CONCLUSION:
After a LADG, the levels of hepatic transaminases were immediately elevated, but returned to normal levels within 72 hours. A LADG with prolonged pneumoperitoneum is considered safe in patients with normal liver function prior to the operation. In addition, to evaluate the safety of a LADG in the patients with decreased hepatic function, a large scaled randomized prospective trial will be required.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pneumoperitônio
/
Neoplasias Gástricas
/
Transferases
/
Bilirrubina
/
Índice de Massa Corporal
/
Estudos Prospectivos
/
Mortalidade
/
Falência Hepática
/
Laparoscopia
/
Ácido Aspártico
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Surgical Society
Ano de publicação:
2007
Tipo de documento:
Artigo
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