A case of eosinophilic perimyositis / 대한내과학회지

ABSTRACT

Eosinophilic perimyositis is an infrequent form of inflammatory muscle disease associated with peripheral blood, bone marrow and/or tissue eosinophilia. The diagnosis is fundamentally based on histological findings. Biopsy of muscle revealed local eosinophilic infiltration into muscle and necrosis of muscle fascicles. Clinical manifestations of eosinophilic perimyositis include myalgia, subcutaneous induration and erythema of skin. There were no consensus on the treatment, but patients with idiopathic eosinophilic myositis have been treated with a variety of modalities, including nonsteroidal antiinflammatory drugs and corticosteroids. Regardless of the treatment, the overall prognosis is good. Eosinophilic myositis was reported in 1980 and rarely thereafter, but there were no case reports in Korea. Recently, we experienced a patient with eosinophilic perimyositis with fibromyalgia and present here with a brief review of the literatures.