The expression of p73 and c-fos protein in hemangioma and its significance / 中华整形外科杂志
Chinese Journal of Plastic Surgery
;
(6): 47-49, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-255106
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the expression of p73 and c-fos protein and its significance in the development of children hemangioma.</p><p><b>METHODS</b>The quantitative expressions of p73 and c-fos protein in hemangioma and normal skin were detected by immunohistochemistry.</p><p><b>RESULTS</b>The expressions of p73 and c-fos protein were strong in proliferative hemangioma while they were very weak in involutional hemangioma and normal skin. There were significant differences between the proliferative and involutional hemangioma or the normal skin in the expressions of p73 and c-fos (P < 0.01). No statistical significances of p73 or c-fos P73 expressions were observed between involutional hemangioma and normal skin (P > 0.05).</p><p><b>CONCLUSIONS</b>P73 and c-fos may play an important role in the development and involution of skin hemangioma.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Proteínas Nucleares
/
Proteínas Proto-Oncogênicas c-fos
/
Proteínas Supressoras de Tumor
/
Proteínas de Ligação a DNA
/
Proteína Tumoral p73
/
Hemangioma
/
Metabolismo
/
Estadiamento de Neoplasias
Limite:
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Lactente
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Plastic Surgery
Ano de publicação:
2005
Tipo de documento:
Artigo
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