Crosstalk between Wnt5a and inflammatory signaling in inflammation / 生理学报
Acta Physiologica Sinica
;
(6): 437-445, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-255928
ABSTRACT
Wnt5a belongs to the large WNT family of cysteine-rich secreted glycoproteins, which is involved in multiple signaling pathways that regulate a variety of cellular processes, including cell motility, proliferation differentiation and so on during development. The regulation and signaling transduction of Wnt5a have been reported to closely relate to inflammatory response, which indicates that Wnt5a plays a critical role in the occurrence and development of inflammatory diseases. In this review, we summarized data on Wnt5a and its signaling pathway, as well as their involvement in inflammatory response. Further comprehensive understanding of the function and relationship between Wnt5a and inflammatory response would help us to develop novel diagnostic and therapeutic strategies for prevention and treatment of inflammatory diseases.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Transdução de Sinais
/
Diferenciação Celular
/
Movimento Celular
/
Proteínas Proto-Oncogênicas
/
Proteínas Wnt
/
Proteína Wnt-5a
/
Inflamação
/
Metabolismo
Limite:
Humanos
Idioma:
Chinês
Revista:
Acta Physiologica Sinica
Ano de publicação:
2015
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS