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Primary research of pharmacological effects of PEC on mice / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 568-593, 2004.
Artigo em Chinês | WPRIM | ID: wpr-256305
ABSTRACT
<p><b>OBJECTIVE</b>To study pharmacological effects of PEC (the oral liquid which consists of Panax quinquefolium, Epimedium brevicornum, Schisandra chinensis Bail and Cervus eplaphus) on mice.</p><p><b>METHOD</b>Experiments were carried out through swimming test, step-through, spontaneous activity and sleeping time.</p><p><b>RESULT</b>When 5-10 mL x kg(-1) of PEC was given orally for 7 days, it could prolong swimming duration of mice in water tank, and increase the tolerant ability against oxygen-deficiency. PEC could also improve cognitive-deficiency induced by taking off sleep with force in mice after given orally for 7 days. The PEC could increase the spontaneous activity in mice, antagonize the inhabitation induced by Valium, and shorten the sleeping time caused by sodium pentobarbital.</p><p><b>CONCLUSION</b>PEC has strong potential neuro-pharmacological activities such as anti-fatigue, improving cognitive-deficiency in mice.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Pentobarbital / Farmacologia / Plantas Medicinais / Sono / Natação / Comportamento Animal / Medicamentos de Ervas Chinesas / Química / Epimedium / Schisandra Limite: Animais Idioma: Chinês Revista: China Journal of Chinese Materia Medica Ano de publicação: 2004 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Pentobarbital / Farmacologia / Plantas Medicinais / Sono / Natação / Comportamento Animal / Medicamentos de Ervas Chinesas / Química / Epimedium / Schisandra Limite: Animais Idioma: Chinês Revista: China Journal of Chinese Materia Medica Ano de publicação: 2004 Tipo de documento: Artigo