Analyses of EGF and TNF contents in fetal wound healing process / 中华整形外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the role of EGF and TNF in the fetal wound healing process.</p><p><b>METHODS</b>On a fetal wound healing model with the maternal rabbit on 22-23 days of pregnancy (term = 31-32 days), the contents of EGF and TNF were analyzed with a RIA kit, compared to the maternal rabbit group and the adult rabbit group.</p><p><b>RESULTS</b>The EGF and TNF contents in the fetal wound were both increasing 3 days after the operation and maintained in a high level until the 7th day of the wound healing process(P < 0.05). However, the EGF and TNF contents in the maternal and adult rabbit groups were only kept at a high level during the 3 days after the surgery.</p><p><b>CONCLUSION</b>The results are indicated that the EGF and TNF may play an important role in fetal wound healing.</p>